Session Nano4Health: Focus on Technologies for Diagnostic purposes
December 2, 11:15-13:00
Microfluidics in a home testing solution
Brigitte Bruijns PhD, Salvitat
During the early days of the COVID-19 pandemic in 2020 five SME’s from East-Netherlands started an initiative together: the VIRAPOC project. Within this project a lab-on-a-chip detection system (MYKEE) has been developed that uses various key enabling technologies. Together, the partners master the competences to develop a widely applicable system with the potential to add various and multiple tests over time. Market segments envisioned span from central laboratory testing over outdoor mass testing to individuals at home.
The MYKEE system is a test solution that consists of a multifunctional, digital connected reader solution with interchangeable cartridges. Each cartridge enables testing a different (set of) analytes. The test platform will be brought to the market by Salivat. The first product to market is a lab-on-a-chip based test system to rapidly diagnose the SARS-CoV-2 virus infection within less than 30 minutes directly from saliva.
In order to determine if someone has been infected with the virus, preferably even before or without the person showing symptoms, it is important to have a very sensitive, specific and rapid test. By using loop mediated isothermal amplification (LAMP), the entire process from sample collection to result can be shortened to less than 30 minutes.
Brigitte Bruijns received her bachelor’s degree in Advanced Technology (University of Twente) in 2007. After that she graduated in 2008 and 2010 for respectively Science Education – Chemistry (University of Twente) and Forensic Science (University of Amsterdam) for which she carried out part of her research project at the University of Canberra, Australia.
As part of her masters in Analytical Sciences (University of Amsterdam/Free University), for which she graduated in 2011, she did her research project in the group of prof. Gardeniers. The project was entitled “Illicit drugs analysis on chip” and had as goal to develop a microfluidic device for a forensic application. She received her PhD in Jan 2019 on the work “Microfluidic devices for presumptive forensic tests”. Thereafter she worked as R&D Scientist at Micronit Microtechnologies. Currently she works as Project Lead Kit Development at Salvitat, as which she is responsible for the sampling method, sample work-up and the cartridge of the MYKEE system.