Nano4Agri&Food Emulsions and up-scaling of microfluidics
December 2, 14:00-15:30
In-air microfluidics for fast and scalable manufacturing of monodisperse microparticles
Tom Kamperman PhD, IamFluidics
Microparticles are everywhere. Products in cosmetics, nutrition, and pharmaceutical markets are nowadays based on or contain microparticles. However, industry is currently facing a limiting trade-off between the quantity and quality of microparticle production. Specifically, traditional bulk production processes based on batch emulsification typically result in polydisperse particles. Microfluidic methods provide highly controlled and monodisperse products, but are severely limited in throughput. Furthermore, complicated chip manufacturing procedures have been hampering wide-spread industrial and clinical application of microfluidics.
Here, I present in-air microfluidics (IAMF), which is a platform technology that enables the chip-free manipulation of microfluidic streams. In concept, microfluidic channels are replaced by micrometer-sized liquid jets that can be combined in mid-air. Via the controlled impact of multiple microjets, this off-chip approach is readily compatible with the production of monodisperse droplets, particles, and fibers at per-nozzle rates that exceed conventional microfluidics up to a 1000-fold. Moreover, IAMF is compatible with solidifying co-flows, which aids the direct deposition of oil-free in-air formed particles. This capacity uniquely enables the one-step additive manufacturing of 3D multiscale modular metamaterials.
Tom Kamperman, PhD
Co-founder & CTO IamFluidics BV
Post-doctoral researcher University of Twente
Tom is an entrepreneurial biomedical engineer with a strong background in microfluidics, tissue engineering, and enabling microtechnologies. He has over eight years of experience with the development of microfluidic systems for life science applications and in particular microencapsulation. He has been working at various internationally recognized institutes including the Max-Planck Institute in Muenster (DE), the MESA+ Institute for Nanotechnology (NL), the Technical Medical Centre (NL), and the Division of Engineering in Medicine at Harvard Medical School (USA). Tom received the ‘Overijssel PhD award’, ‘NBTE PhD thesis award’, and ‘DutchBiophysics BIOPM thesis award’ for his PhD thesis titled ‘Microgel Technology to Advance Modular Tissue Engineering’. In 2019, he was elected “European Innovator Under 35” by MIT Technology Review. Tom is co-inventor of the ‘in-air microfluidics’ technology and co-founder of the company IamFluidics BV, where he is responsible for technical management and product development. Tom is currently also affiliated as a post-doctoral researcher at the University of Twente, where he is working on single cell encapsulation to protect cells during 3D bioprinting.