Miniaturization in nanotechnology
December 3, 9:45-11:15
Super-resolution microscopy through an ultra-thin fiber probe
Dr. Lyuba Amitonova, Advanced Research Center for Nanolithography (ARCNL)
Endoscopy is a key technology for minimally-invasive optical access to any hard-to-reach places. The thin and flexible nature of optical fibers makes them the ideal imaging tool for many applications, ranging from nanolithography to life sciences. However, state-of-the-art endo-microscopy still has many limitations: the spatial resolution is controlled by the diffraction of light and the imaging speed follows the Nyquist-Shannon sampling theorem. By using advanced computational methods and the exponential growth of computing power we were able to revolutionize imaging rethinking both the optical design and the post-processing.
I will show how computational methods push the boundaries of optical endo-microscopy and provide imaging beyond the Abbe and Nyquist limits through a miniature fiber endoscope. The new approach is based on random light scattering in a multimode fiber, the sparsity constraint and compressive sensing reconstruction algorithms. We demonstrate spatial resolution more than 2 times better than the diffraction limit and simultaneously overcome the Nyquist limit by reconstructing an N-pixel image from less than N/20 single-point measurements.
Dr. Lyuba Amitonova is currently a group leader at Advanced Research Center for Nanolithography (ARCNL) and a tenure-track assistant professor at Vrije University (VU) Amsterdam. Lyuba received her PhD from the Lomonosov Moscow State University (Russia) back in 2013. As a postdoc, she worked at the Russian National Research Center “Kurchatov Institute” (Moscow, Russia) and at the University of Twente (Enschede, the Netherlands) where she worked on advanced manipulation and propagation of light and successfully applied wavefront shaping for imaging, endoscopy, and quantum communication. She received multiple grants and prices: personal grants from Russian Foundation for Basic Research, VENI and WISE grants from NWO. She has published over 30 peer reviewed papers.